Potato early die complex (PED) is an annual concern for commercial potato growers and is a particular problem in Idaho as yield losses of up to 50% can occur in sandy soils although 20-30% losses are more usual. The primary causal agent of PED is Verticillium dahliae and although PED can occur from V. dahliae infection alone, earlier onset occurs when V. dahliae and the root lesion nematode (Pratylenchus spp.) are both present. In addition, other causal agents have been implicated in the early die complex including Colletotrichum coccodes, Botytis cinerea and Fusarium oxysporum. The use of soil fumigation is an effective tool for the management of PED in potato. While the U.S. industry is dependent on fumigation to produce a marketable crop with maximum yields, society is pushing towards a reduction in soil fumigation. A two-year trial is currently underway to identify potato varieties with enhanced resistance and biopesticides/fungicides that effectively manage the early die complex. In 2024 a variety x fungicide trial was carried out to investigate conventional and biofungicide spray programs in conjunction with two different varieties, Ranger russet, and Huckleberry gold for efficacy against PED. PED symptoms were rated visually, and soil and plant stems were collected for qPCR analysis. Results showed that all fungicide programs tested had significantly lower levels of PED compared to the untreated control. Levels of PED were significantly lower in Ranger russet than Huckleberry gold and in half of the programs, treatment with fungicides significantly increased yields.